Cialis Together for Erectile Dysfunction

Cialis Together tablets are a treatment for adult men who have erection problems (erectile dysfunction). This is when a man cannot get, or keep an erection hard enough for satisfactory sexual activity.

Cialis Together tablets contain the active substance tadalafil. It belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing the blood vessels in your penis, allowing blood flow into your penis.

It is important to know that you will not get an erection just by taking Cialis Together tablets. This medicine works with your body’s natural function to get an erection only when you are sexually stimulated.

Cialis Together contains the active ingredient Tadalafil. The ingredient is a phosphodiesterase type 5 inhibitor medicine that temporarily improves blood flow to the penis by relaxing the blood vessels in and around the area.

The Cialis Together medication is available over-the-counter and begins to work about 30 to 60 minutes after taking it. The effects are expected to last up to 36 hours. Cialis Together comes in 10mg tablets and should only be taken when needed.

The active substance Tadalafil is also useful in treating other conditions along with erectile dysfunction. Please consult a Doctor, a Pharmacist or relevant product literature for more information.

Is Cialis Together right for me?

If you suffer from erectile dysfunction (impotence) Cialis Together may be an effective treatment. However, it may not be suitable for you if you have the following:

• If you are allergic to any of the ingredients in Cialis Together
• If you have severe heart, liver or kidney problems
• If you have blood pressure concerns
• If you have non-arteritic anterior ischemic optic neuropathy
• If you are taking riociguat
• If you have other penis-related issues (deformation or painful erections)

Also, if you have severe heart, liver or kidney problems or meet the following:

• If you have any heart problems or have a history of them.
• If you have any liver problems or you have a history of it.
• If you are taking sildenafil for non-arteritic anterior ischemic optic neuropathy (NAION)
• If you have high blood pressure you should be closely monitored by your doctor before taking Cialis Together.
• If you are taking riociguat or other nitrates you should not take Cialis Together.
• If you are taking the following blood pressure/cardiologics: riociguat (tazuma), angiotensin converting enzyme (ACE) inhibitors (such as ‘ guanylate cyclase stimulators’), like mifepristone or riociguat
• If you are taking any other type of medication (including non-prescription oral medication)
• If you are pregnant or you plan to become pregnant, or you are breastfeeding or you are taking oral contraceptive pills, Cialis Together may only be takenCialis Together is not suitable for use in women.
• If you have any medical conditions, like breast cancer or the potential for blood clots Cialis Together may not be suitable for you
• If you have the following, you should be aware before taking Cialis Together
• Taking tadalafil for the prevention of pulmonary hypertension Cialis Together is not safe when taken for the treatment of erectile dysfunction.
• Cialis Together may not be suitable for some people like you.
• Before taking the pill ask your doctor or the doctor who are your local pharmacy or your doctor ().
• If you are over 18 years of age or older
• If you are currently currently breastfeeding or you are planning to breastfeed or plan to use food.
• Cialis Together is not suitable for you if you have pulmonary arterial hypertension or any other heart, liver or kidney problems.
• Pulmonary arterial hypertension and other heart, liver and kidney problems depending on your age.
• Cialis Together may not be suitable for you if you have any cardiac problems, like a heart attack or if you are a woman.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

• Ketoconazole, itraconazole (used to manage fungal infection)
• Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
• Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
• Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
• Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

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C.

Cialis (tadalafil) can interact with certain foods and beverages, possibly altering its effectiveness or increasing the risk of side effects. Here are the key drug-food Interactions:

1. : ANGLOAP® (flavacon, tetracycline)
2. : Though not a direct interaction, combining Cialis with grapefruit and grapefruit juice might significantly enhance the blood pressure-lowering effects of the medication, making Cialis a more suitable choice for male patients with conditions such as hypertension, who use excessive grapefruit consumption as aACHG
3. : While Tadalafil can be taken with or without food, consuming it with a high-fat meal may delay its onset of action Ex. Cialis.

Are you looking for a chance to regain confidence and have a fulfilling intimate life? Medication can offer hope and symptom improvement for more control over your health. There are many, but two leading treatments, sildenafil (Viagra®) and tadalafil (Cialis®), could offer the results you have been looking for. Learn more here about how they work, what sets them apart and which medication might be better for ED in your unique situation.

What is sildenafil (Viagra®)?

, a generic version of, belongs to a class of medications called phosphodiesterase (PDE) inhibitors. It treats erectile dysfunction, 1 and pulmonary arterial hypertension (PAH).2 For ED, it works by relaxing blood vessels and increasing blood flow, which can help achieve erection with sexual stimulation.3

Sildenafil is an oral medication that takes approximately 30 minutes to take effect after ingestion. The effects last around four hours on average.4 Commonly prescribed doses range from 20 mg to 100 mg, with 50 mg being utilized the most. Suggested use is as needed, with no more than one dose per day.5

What is tadalafil (Cialis®)?

, a generic version of, is also a PDE inhibitor used to treat ED, PE6 and PAH. For erectile dysfunction, oral medication increases blood flow to cause an erection with a sexual stimulus.7

The dosage depends on if tadalafil is being used as needed or daily as an ED maintenance treatment. As needed dosage is commonly 10 mg once per day as needed before sexual activity. Users can continue treatment as needed with 5 mg to 20 mg before sexual activity. On average, it takes around 30 to 45 minutes for tadalafil to take effect.8 However, it can take up to two hours in some cases.9 The effects can last up to 36 hours.10

For long-term treatment of ED, 2.5 mg per day is the common dosage, regardless of when sexual activity occurs. Maintenance on this regimen ranges from 2.5 mg to 5 mg daily.11

What are the differences between sildenafil and tadalafil?

Both sildenafil and tadalafil are PDE inhibitors with similar mechanisms of action, but there are some differences. The main difference between the two medications is the time to take effect and the duration of effect.

Sildenafil is more often recommended for spontaneous use. It takes about 30 minutes to take effect and lasts around five hours. While for some users, the effects can start as soon as 30 minutes. However, recommended advice is to allow tadalafil approximately two hours before sexual activity for best results. Tadalafil effects can last up to 36 hours after ingestion making it suited for long-term use.12

How effective are sildenafil and tadalafil for erectile dysfunction?

PDE inhibitors, like sildenafil and tadalafil, have a promising success rate. There have been reported success rates in studies of up to 70% when using PDE inhibitors for ED.13

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How do the side effects compare for sildenafil and tadalafil?

Sildenafil and tadalafil have several common side effects, including headache, heartburn, diarrhea, nausea, flushing and muscle pain.

Side effects unique to sildenafil include:14

• Nosebleeds

• Numbness, burning, or tingling in the arms, hands, feet or legs

• Changes in color vision sensitivity to light

• Nasal congestion

Side effects unique to tadalafil include:15

What are common drug interactions for sildenafil and tadalafil?

Many medications can interact with sildenafil or tadalafil, and this list is not exhaustive.

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